After treatment, the mice’s memories were essentially shunted back into a younger state. The researchers found that reprogrammed engrams displayed molecular behavior of more youthful cells. Using a ...

Disease progression after intensive multi modal clinical therapy poses grave concern not only on the quality of life but on the very survival of children presented with neuroblastoma. Acquired ...

For decades, scientists have worked to peer deeper into the brain. They have wanted to see not just surface activity in the cortex but also the hidden layers beneath, such as the hippocampus, where ...

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible. But the brain is not static; neurons continually adjust the strength of their ...

Researchers identify "Otp" as a molecular switch in the brain that determines the balance of hunger and satiety neurons, shaping lifelong obesity risk.

Your brain relies on glucose to function correctly. This means that your mind and focus may be impacted if your blood sugar ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study led by ...

Researchers have uncovered how metabolic reprogramming contributes to renal fibrosis in IgG4-related disease (IgG4-RD), a systemic immune-mediated disorder. The review, published in a leading journal, ...

Tumor growth unfolds within a tumor microenvironment (TME) defined by metabolic–immune crosstalk. Emerging evidence indicates that cancer cells not only reprogram glycolysis but also alter amino acid, ...

Researchers at UT Southwestern Medical Center have discovered that a crucial developmental process in the brain's ...