Biopharmaceutical production depends on buffers. Making sure the right buffer solutions are available, in the right place on the manufacturing line, at the right time, and in the right quantity, is a ...

In-line buffer management markedly reduced the production bottlenecks and manufacturing costs inherent in biopharmaceutical manufacturing. Additional cost reductions are possible, however, by ...

In this installment, I primarily discuss considerations to keep in mind when choosing buffering additives that will be used for LC methods involving UV absorbance detection. Buffered solutions that ...

This lab includes a theoretical explanation of how buffers work and how they are made, including a derivation of the Henderson-Hasselbalch equation. Students will use what they have learned to ...

Recently, the trend of outsourcing buffer manufacturing system has been adopted by pharmaceutical companies as it reduces the cost of buffer formulation, eliminates space and temperature maintenance ...

This paper reports the results for the pH of three buffer solutions free of chloride ion. The remaining six buffer solutions have saline media of the ionic strength I = 0.16 mol.kg-1, matching closely ...