Scientists have unearthed 188 previously unknown types of CRISPR systems buried in the genomes of simple microorganisms. Best known as a powerful gene-editing tool, CRISPR actually comes from an ...

Researchers identified AlCas12a, a compact, versatile enzyme that improves CRISPR gene editing and enables faster molecular ...

CRISPR—Clustered Regularly Interspaced Short Palindromic Repeats—is the microbial world’s answer to adaptive immunity. Bacteria don’t generate antibodies when they are invaded by a pathogen and then ...

Microbiologist John van der Oost of Wageningen University & Research (WUR) has received an ERC Proof of Concept grant to further develop a promising CRISPR-based approach to cancer treatment. With ...

Researchers in Spain have resurrected ancient CRISPR proteins from millions and even billions of years ago. Not only can they still edit human cells, but they’re more versatile than modern versions, ...

For decades, scientists have studied how to control DNA—the molecule that holds the instructions for all life. One of the most powerful tools to emerge from that effort was CRISPR, a system adapted ...

Many genetic diseases are caused by diverse mutations spread across an entire gene, and designing genome editing approaches for each patient's mutation would be impractical and costly. Many genetic ...

When the genome-editing tool CRISPR is thought of as a potential medicine, the targets that first come to mind are diseases like sickle cell or other conditions caused by particular mutations. Use ...

CRISPR systems are powerful tools for genetic engineering, but they have their limitations. Now, scientists have discovered almost 200 new CRISPR systems in their native habitat of bacteria, and found ...

The CRISPR system, which involves a Cas enzyme to cut DNA, is a powerful tool for gene editing. But the genetic scissors sometimes make changes at the wrong place, creating a major safety problem that ...