To protect themselves against viral infection, bacteria often use CRISPR-Cas systems to identify and destroy an invading virus’s genetic material. But viruses aren’t helpless and can deploy ...

Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...

Scientists introduced CRISPR to the world as a gene-editing tool in summer 2012, when landmark papers from two independent groups demonstrated how the system could be wielded to make cuts in DNA. Now, ...

Researchers at Utah State University revealed new details about CRISPR immune system defenses, such as Cas12a3 systems, that ...

An innovative genome-editing tool promises to do what original CRISPR systems have struggled to achieve: insert entire genes, precisely and efficiently, into human DNA. “It could really be a big part ...

CRISPR-Cas systems are bacterial adaptive immune systems that target and cut the nucleic acids (DNA/RNA) of invading genetic parasites like bacteriophages (phages); viruses that infect - and ...

Small and precise: These are the ideal characteristics for CRISPR systems, the Nobel-prize winning technology used to edit nucleic acids like RNA and DNA. Rice University scientists have described in ...

A new search algorithm has identified 188 kinds of new rare CRISPR systems in bacterial genomes, encompassing thousands of individual systems. The tool, which comes from the lab of CRISPR pioneer Feng ...

Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins are core components of fast-evolving therapeutic gene editing tools. Scientists have used CRISPR ...

The evolutionary pathway connecting the OMEGA system to the CRISPR system. The review paper "CRISPR Beyond: Harnessing Compact RNA-Guided Endonucleases for Enhanced Genome Editing," authored by Feizuo ...