Our bodies are made up of about a hundred million million (100,000,000,000,000) tiny cells. You can only see them under a microscope. Cells group themselves together to make up the tissues and organs ...

Advancements in spatial proteomics enable detailed tissue mapping, linking protein localization to disease mechanisms and ...

Dissociating tissues into single cells is a core laboratory technique and vital for widely used applications such as next-generation sequencing or flow cytometry. Scientists who employ tissue ...

In recent research published in Nature Communications, scientists investigated the role of cell density – how closely cells are packed in a given space – in forming multicellular structures. The study ...

Epithelial tissues are in constant interaction with their environment. Maintaining their functionality requires dynamic balance (homeostasis) and that their cell numbers are tightly regulated. This is ...

Advanced in vitro models such as organ-on-chip systems aim to replicate human physiology more accurately than conventional cell cultures. However, most existing platforms struggle to incorporate ...

Intercellular forces generate distinct patterns of extrusion: high compressive forces (top panel) drive apoptotic cell extrusion toward the upper side, while lower compressive forces (bottom panel) ...

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität ...