DNA coding theory bridges the disciplines of mathematics, computer science and molecular biology by applying advanced algebraic and combinatorial techniques to the design of nucleotide sequences. This ...

St. Jude Children’s Research Hospital scientists have identified specific DNA variants in the non-coding regions of the genome contributing to chemotherapy resistance in acute lymphoblastic leukemia ...

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

The accumulation of mutations in DNA is often mentioned as an explanation for the ageing process, but it remains just one hypothesis among many. A team from the University of Geneva (UNIGE), in ...

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...

Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

But only a tiny percentage of our DNA – around 2% – contains our 20,000-odd genes. The remaining 98% – long known as the non-coding genome, or so-called ‘junk’ DNA – includes many of the switches that ...

DNA is often compared to a written language. The metaphor leaps out: Like letters of the alphabet, molecules (the nucleotide bases A, T, C and G, for adenine, thymine, cytosine and guanine) are ...