Activation of the complement system through the alternative pathway is necessary for the development of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in animal models C5a has ...

1 Department of Pharmaceutical Sciences, College of Pharmacy, Texas A&M University, Kingsville, TX, United States 2 Department of Pharmacy Practice, College of Pharmacy, Texas A&M University, ...

Neuroinflammation is associated with a wide spectrum of acute and chronic diseases of the central and peripheral nervous system. It causes secondary damage, which is a major determinant for ...

Long Covid patients face ongoing issues like tiredness and difficulty breathing. Researchers from the University of Zurich and University Hospital Zurich found that the complement system, a part of ...

The mammalian immune system is a remarkable complex of biochemical processes enabling efficient detection and prosecution of pathogens that threaten host viability. The incredible complexity of ...

The complement system plays an important role in the etiology of many autoimmune diseases, including cold agglutinin disease (CAD), a subset of autoimmune hemolytic anemia. In CAD, auto-antibodies ...

The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes ...

Researchers at the National Eye Institute have found that the complement system seems to protect against retinal degeneration in retinitis pigmentosa. The research contradicts previous findings, which ...

Most people infected with the SARS-CoV-2 virus recover after the acute illness. However, a significant proportion of infected individuals develop long-lasting symptoms with a wide range of ...