Proceedings of the National Academy of Sciences of the United States of America, Vol. 64, No. 4 (Dec. 15, 1969), pp. 1284-1291 (8 pages) Complementation analysis at the single gene level has been ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 76, No. 12 (Dec., 1979), pp. 6520-6524 (5 pages) A whole-cell microtechnique for the determination of ...

We have devised a general strategy for producing female mice from 39,X0 embryonic stem (ES) cells derived from male cell lines carrying a targeted mutation of interest. We show that the Y chromosome ...

Protein interactions integrate stimuli from different signaling pathways and developmental programs. Bimolecular fluorescence complementation (BiFC) analysis has been developed for visualization of ...

Complementation analysis at the single gene level has been carried out on 13 different, recessive, glycine-requiring mutants produced by action of mutagenic agents on the CHO-K1 Chinese hamster cell.

We present a yeast chemical-genomics approach designed to identify genes that when mutated confer drug resistance, thereby providing insight about the modes of action of compounds. We developed a ...