In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed ...

In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues have used mitochondrial base editing (mtBE) to successfully edit harmful ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Researchers at The University of Texas MD Anderson Cancer Center have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

A landmark study by WEHI scientists has shed new light on one of the most fundamental mysteries of biology: how cells divide and grow into the complex structures that make up our bodies. The study has ...

Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about 0.01 mm in size, it must be tightly folded. DNA wraps around proteins call ...