The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both sides of the DNA helix are cut at once. Healthy cells can normally fix ...

Since its breakthrough development more than a decade ago, CRISPR has revolutionized DNA editing across a broad range of fields. Now scientists are applying the technology's immense potential to human ...

Proteins PIF1 and PCNA gather at sites of DNA damage in SETX-deficient cells, indicating activation of the BIR repair system. LA JOLLA, CA—The DNA inside our cells is constantly being damaged, and one ...

A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most ...

Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer. Their study, published in Nature, uncovered a brand ...

Scientists have made a major discovery about how cells repair broken strands of DNA that could have huge implications for the treatment of cancer. Their study, published in Nature today (Wednesday), ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

Scientists from the Kavli Institute of Nanoscience at Delft University of Technology have discovered a key element in the mechanism of DNA repair. When the DNA double helix breaks, the broken end goes ...