To gain a deeper understanding of BKPyV replication and ways to prevent it, UAB researchers in the Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney ...

DNA replication is happening continuously throughout the body, as many as trillions of times per day. Whenever a cell divides—whether to repair damaged tissue, replace old cells, or simply to help the ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research reveals new aspects of BKPyV replication, offering possible drug targets ...

DNA contains foundational information needed to sustain life. Understanding how this information is stored and organized has been one of the greatest scientific challenges of the last century. With ...

Dr Peter Martin leads a highly collaborative research project, that explores the role of the multi-functional replication checkpoint protein topoisomerase beta binding protein 1 (TOPBP1) in mitosis.