Sepsis is a life-threatening condition that often leads to ARDS, characterized by widespread inflammation and vascular injury. This study identifies lactate-driven lysine lactylation (Kla) as a ...

Empagliflozin reduced proinflammatory cytokines and oxidative stress markers in INOCA patients with CMD, improving vascular health. Treatment led to favorable shifts in endothelial extracellular ...

In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like ...

The endothelial glycocalyx integrates mechanical signals with vascular biology, playing a vital role in health and disease, ...

Scientists show how a common zero-calorie sweetener found in many diet drinks may harm the brain's vascular system by increasing oxidative stress and impairing vital blood vessel functions. Study: The ...