The endothelial glycocalyx integrates mechanical signals with vascular biology, playing a vital role in health and disease, ...

BACKGROUND: The disruption of the blood–brain barrier (BBB) is a central pathogenic event in many central nervous system disorders. However, the mechanisms regulating BBB function remain incompletely ...

Cells in humans and all vertebrates are tightly packed together to form organs and glands — tissues essential for living, breathing and moving. The narrow spaces between cells represent natural weak ...

Research in animal models has demonstrated that stem-cell derived heart tissues have promising potential for therapeutic applications to treat cardiac disease. But before such therapies are viable and ...

The vascular endothelium represents a monolayer of endothelial cells that envelops the innermost surfaces of arteries, veins, cardiac lumina, and lymphatic vessels. These endothelial cells are ...

Corneal transplantation using donor tissue is currently the primary treatment for corneal endothelial insufficiency. Despite the potential for vision restoration through corneal transplantation, there ...