Scientists of the German Center for Diabetes Research (DZD) led by the German Institute of Human Nutrition (DIfE) have shown in a mouse model that the epigenetic modification of the Igfbp2 gene ...

Researchers have discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development. This finding ...

During the process of metastasis, tumor cells inevitably encounter the stimulation of various oxidative stressors, resulting in the fluctuation of intracellular reactive oxygen species (ROS) levels.

Working model of the BrHDA6-BrSOT12 module in downy mildew resistance of B. rapa.

Researchers at the Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences have obtained important data on the effect of DNA methylation on long-term synaptic ...

While each cell contains the complete genetic blueprint of an organism, chemical marks on the DNA – so-called epigenetic modifications – control which genes are active when and where. A team led by ...

The team of Prof. Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine functions as an activating epigenetic ...

This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...

Downy mildew is a major constraint on Brassica crop production worldwide, especially during early developmental stages when ...