Many response variables are handled poorly by regression models when the errors are assumed to be normally distributed. For example, modeling the state damaged/not damaged of cells after treated with ...

In this module, we will introduce generalized linear models (GLMs) through the study of binomial data. In particular, we will motivate the need for GLMs; introduce the binomial regression model, ...

Linear mixed model (LMM) methodology is a powerful technology to analyze models containing both the fixed and random effects. The model was first proposed to estimate genetic parameters for unbalanced ...

Genome-wide association studies (GWAS) are widely used to uncover novel genetic susceptibility loci for complex genetic diseases. If the true genetic model is known, the association test reflecting ...

This paper proposes Bayesian nonparametric mixing for some well-known and popular models. The distribution of the observations is assumed to contain an unknown mixed effects term which includes a ...

Various methods have been proposed for smoothing under the monotonicity constraint. We review the literature and implement an approach of monotone smoothing with B-splines for a generalized linear ...