To test our hypothesis, that localized antagonism of the AT 1 R at upper thoracic spinal segments would decrease CSNA without altering mean arterial pressure (MAP) in ovine HF, we infused losartan ...

The cerebrospinal fluid in examinations 20–24 was a sample kept from the drainage tube on the lumbar cistern, for which the pressure could Damage to the cranial nerve occurred when the intrathecal ...

Study design: Intrathecal administration of 4-aminopyridine (4-AP) in chronic spinal cord injured (SCI) patients. Objective: To determine the safety and effects of intrathecal administration of 4-AP ...

Background and objectives: X-linked adrenomyeloneuropathy (AMN) is an inherited neurodegenerative disorder associated with mutations in the ABCD1 gene and the ...

THE treatment of spinal block occurring in tuberculous meningitis has been unsatisfactory. Recently, however, Smith 1–3 has reported successful results in such cases with the intrathecal ...

The objective of the study was to retrospectively evaluate the short-term safety of intrathecal administration of cytosine arabinoside alone or in combination with methotrexate in dogs and cats. One ...

THE neurologic manifestations of Central-nervous-system involvement in acute leukemia have been very well described. 1–7 Although involvement of the brain is not rare 7,8 greater emphasis has been ...

A novel indwelling subcutaneous intrathecal catheter circumvented the complex spine anatomy of patients with spinal muscular atrophy (SMA), a challenge when giving nusinersen via intrathecal injection ...

In a recent study published in Nanomedicine: Nanotechnology, Biology and Medicine, researchers evaluated the biodistribution of cannabidiol (CBD) emulsion and nanoparticles in the central nervous ...