Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor, new research finds. The interrupted non-coding regions in pre-mRNAs, termed ...
Pre-mRNA splicing in a subset of human short introns is governed by a distinct mechanism involving a new splicing factor Protein-coding genes carry the blueprint for protein production. In higher ...
RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions ...
RNA splicing is a post-transcriptional modification process that occurs in eukaryotic cells. When a gene is transcribed, the initial RNA product is called pre-mRNA, which contains both coding regions ...
Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been ...
The interrupted non-coding regions in pre-mRNAs, termed “introns,” are excised by “splicing” to generate mature coding mRNAs that are translated into proteins. As human pre-mRNA introns vary in length ...
Our cells have to generate a massive number of proteins, and there is a carefully orchestrated procedure for doing so. It starts when active genes are transcribed into RNA, and while that RNA ...
Cold Spring Harbor, NY - No one knows how many times in a day, or even an hour, the trillions of cells in our body need to make proteins. But we do know that it's going on all the time, on a massive ...
Alison Tang (UC Santa Cruz) describes her lab’s studies on full-length transcript characterization of the mutated SF3B1 transcriptome in chronic lymphocytic leukemia Sponsored content brought to you ...
While some details of the mechanisms of splicing remain to be worked out, it’s known that mature, edited mRNAs result from an interplay between multiple factors within and outside the transcript ...