Leukocyte adhesion deficiency (LAD) type III is a rare syndrome characterized by severe recurrent infections, leukocytosis and increased bleeding tendency. All integrins are normally expressed; yet, a ...

Recruitment of leukocytes from the vasculature to sites of inflammation involves a highly regulated interplay between adhesion molecules and their ligands. During the recruitment process, circulating ...

The movement of leukocytes from the circulatory system to the site of inflammation and subsequent attachment forms an integral part of the innate immune system. The three steps of leukocyte rolling, ...