Despite the contributions of more than 700,000 men to randomized controlled trials (RCTs) of prostate cancer (PC) screening over several decades, it is still unclear whether there is a PC-specific ...

Phenotypic screening is a drug discovery approach that identifies bioactive compounds based on their ability to alter a cell or organism’s phenotype (observable characteristics) in a desired manner.

Virtual screening can be approached in several ways, depending on whether the comparison is based on the known small molecule binders (ligands) or the target protein structure. Ligand-based virtual ...