MONTREAL — Levels of neurofilament light chain (Nfl) may be a biomarker of chemotherapy-induced peripheral neurotoxicity (PIPN), new research suggests. Investigators found Nfl levels increased in ...

In a recent study published in the journal Nature, researchers investigate whether pairs of unrelated B-cells of naive, unswitched, memory and plasmablast phenotypes that have similar heavy chains ...

Ikoma, Japan – Antibodies (immunoglobulins) are Y-shaped proteins that recognize and neutralize specific pathogens. Their ability to target specific molecules or cells has made them promising ...

When Sally Cox was diagnosed with light chain amyloidosis (AL) in 2019, she was shocked. Not only had she never heard of the rare disease that causes abnormal proteins (or amyloids) to build up in ...

AL (immunoglobulin light chain) amyloidosis is a rare disease that often results in progressive organ dysfunction, organ failure and eventual death. Clonal plasma cells in the bone marrow secrete free ...

MM often goes undetected until its later stages because it presents with non-specific symptoms, including fatigue, weight loss, bone pain, and recurrent infections. 2,3 However, better awareness, ...