Advances in material science combined with nanofabrication and computational design have led to the discovery of label-free protein microarray techniques. These techniques are of enormous benefit for ...
Researchers have invented a technique in which DNA assays -- the key to personalized medicine -- can be read and evaluated with no need of elaborate chemical labeling or sophisticated instrumentation.
BERKELEY, CA — The dream of personalized medicine — in which diagnostics, risk predictions and treatment decisions are based on a patient's genetic profile — may be on the verge of being expanded ...
A new palm-sized microarray that holds 1,200 individual cultures of fungi or bacteria could enable faster, more efficient drug discovery, according to a study published in mBio®, the online ...
High-throughput RNAi screening is widely applied in biological research, but remains expensive, infrastructure-intensive and conversion of many assays to HTS applications in microplate format is not ...
Physicists at the Georgia Institute of Technology have demonstrated a new optical technique for controlling the flow of very small volumes of fluids over solid surfaces. The technique, which relies on ...
Progress in biology is driven in part by technology, and periodically a new technology enters the scene that radically transforms laboratory investigation. When such landmark technologies first appear ...
Based on electrostatic repulsion — in which objects with the same electrical charge repel one another — the technique is relatively simple and inexpensive to implement, and can be carried out in a ...
Microarrays have been critical components of biomedical and clinical research strategies since their first mention in a 1995 study. Initially designed to measure gene expression, or transcription, ...
A new study published in the journal mBio reports on a palm-sized microarray that can hold more than 1,200 individual cultures of fungi or bacteria and enable faster and more efficient drug discovery.
Current microarray analysis uses 'chips' containing either 25-residue oligonucleotides synthesized by photolithography or cDNAs placed by robotic spotting. In the April Nature Biotechnology, Hughes et ...