Reactive oxygen species (ROS) were long regarded as harmful by-products of mitochondrial metabolism, but growing evidence—including our own—shows that ROS also signal to core processes such as ...

Supersulfides play a fundamental role in longevity: maintaining protein folding in the endoplasmic reticulum (ER) and energy production in mitochondria. Ikoma, Japan – Supersulfides are gaining ...

Supersulfides, many of which are produced by cysteinyl-tRNA synthetase (CARS), are essential compounds across many different lifeforms. However, the precise physiological roles of CARS-produced ...

Traditionally referred to as the powerhouses of cells, mitochondria play a vital role in the conversion of food into energy for biological processes in cell biology. However, in recent years, a ...

Ultrafine particles, UFPs, the smallest contributors to air pollution, hinder the function of mitochondria in human olfactory mucosa cells, a new study shows. The study showed that traffic-related ...

Study findings map out a new way in which antiviral signals engage with cellular metabolism to balance defense and repair.

When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory ...

Scientists have uncovered a previously unseen protein interaction that appears to accelerate Parkinson’s disease by undermining the brain’s energy systems, offering what researchers describe as a ...