At the onset of diabetic cardiomyopathy, Trdn-as expression increases, which regulates the methylation of Casq2 mRNA mediated by METTL14, thus increasing the stability and expression of Casq2 mRNA.

Advanced imaging technology captures translation of the maternal genome. [A. Amunts and D. Nowakowski] Researchers from Finland, Sweden, the U.K., and the U.S. say they have captured ribosomes ...

Mitochondria are known as the powerhouses of the cell, generating the energy that’s needed to fuel the functions that our cells carry out. Now, scientists at the Salk Institute and the University of ...

Mitochondria in the fat tissue of mice unable to produce SLC35A4-MP, causing the mitochondria to be structurally compromised and dysfunctional. LA JOLLA (August 29, 2025)—Like bees breathing life into ...

As we age, we lose bits of our genome in tissues such as the skeletal muscle and the brain. These losses, called deletion mutations, gradually erode the function of a cell component called the ...

Scientists have taken a closer look at how mitochondria are maintained in nondividing cells, such as neurons, with the ultimate goal of developing a better understanding of how to prevent or treat age ...

Mitochondria are known as the powerhouses of the cell, generating the energy that's needed to fuel the functions that our cells carry out. Now, scientists at the Salk Institute and the University of ...

Study uncovers a polyphenol's mechanism in enhancing mitochondrial calcium uptake and muscle bioenergetics during aging. Study: Mitochondrial calcium uptake declines during aging and is directly ...