Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA Figure 2. Potential roles of NADPH oxidase in antigen presentation. MHC-I and MHC-II are both ...

The economically efficient utilization of NAD(P)H-dependent enzymes requires the regeneration of consumed reduction equivalents. Classically, this is done by substrate supplementation, and if ...

NADPH oxidases (NOX) are transmembrane proteins, widely spread in eukaryotes and prokaryotes, that produce reactive oxygen species (ROS). Eukaryotes use the ROS products for innate immune defense and ...

ABSTRACT: Background: Glucose is the main substrate for the generation of NADPH, the cofactor of the oxidative burst enzyme NADPH-oxidase of blood neutrophils. Changes in blood glucose are thus ...