Researchers have conducted the most comprehensive analysis to date linking plasma proteins to genetic variation in ...

Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire network of RNA-protein interactions inside human cells — an achievement that ...

Ahmet Coskun's lab has developed iseqPLA to map protein interactions. An artistic rendering of sub-cellular activity: The cell membrane is seen at the top, nucleus on the bottom/right. Protein pairs ...

The decline of brain endothelial cell (BEC) function, due to aging, is a contributor to neurological disease. BECs lining the inner walls of blood vessels regulate the exchange of molecules across the ...

Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceuticals, including protein-based therapies, require extensive characterization, ...

Misfolded proteins can appear as small aggregates, soluble monomers, or large insoluble inclusion bodies. While the fundamental biophysical mechanisms that cause cytotoxicity are not fully understood, ...

Tissues are where most biological functions, drug effects and diseases occur, and are often considered a homogenous entity where different types of cells are woven in regularly repeated patterns.