In summary, macrophages secrete IFN-β, activating the IFN-β-IFNAR-p-STAT1 axis in MICFs, leading to increased secretion of CCL2/7/12 chemokines and subsequent recruitment of more IFN-β-secreting ...

Researchers created hybrid macrophages that support multiple stages of bone healing, including regeneration and ...

Cancer incidence rises sharply with age, yet the biological mechanisms that make older patients more vulnerable to treatment failure remain poorly ...

A team led by researchers has discovered that a group of cells located in the skin and other areas of the body, called neural crest stem cells, are the source of reprogrammed neurons found by other ...

Cellular reprogramming, when the identity and function of a cell changes, results in the cell acquiring embryonic stem cell pluripotency. This process requires gene expression patterns changes, ...

Gram-stained section of a macrophage with ingested S epidermidis bacteria, seen as purple granules within its cytoplasm. In this stain, the nucleus appears pale, with a reddish nucleolus. It is ...

Researchers from Monash University in Melbourne and The University of Western Australia have demonstrated how a reprogramming method imitates embryonic epigenetic reset. Transient naive treatment (TNT ...

A mature cell of one type can be turned into a mature cell of another type without the cell having to pass through an earlier stage of development. This is called direct reprogramming, a reliable but ...