AZoLifeSciences on MSN
Natural molecular brake prevents uncontrolled DNA replication in cells
For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...
A study shows how scientists can control cell division on demand outside of a living system. The work is a significant leap forward that can enhance our grasp of human biology and disease. A living ...
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A starting signal for cell division: Molecular switch ensures that cells divide at the right time
About 100 cells divide every second in our body. A key protein in cell division is a protein kinase termed Plk1, because it activates other proteins involved in this process. Plk1 is also ...
If measured from beginning to end, the DNA in our cells is too long to fit into the cell’s nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the ...
Cell division is an essential process for all life on Earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive—particularly for egg-laying species ...
The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...
Like all forms of cancer, lung cancer is defined by uncontrolled cell division caused by loss of physiological tissue homeostasis and failure of apoptotic cell death mechanisms. Aberrant cell ...
Researcher are now able to rebuild the switch that remodel the cytoskeleton. Images of an anaphase cytoskeleton in a dividing cell (left) and when rebuilt in vitro (right). PRC1 (green) crosslinks ...
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