Fractures play an important role as flow paths in porous media. When an undersaturated reactive fluid is flowing in a fracture, the dissolution process will alter the flow paths locally. Dissolution ...

Amorphous solid dispersions (ASDs) are of great interest as enabling formulations because of their ability to increase the bioavailability of poorly soluble drugs. However, the dissolution of these ...

This project aims to investigate the release performance of bilayer tablet (BL-Tablet) designed with both fast and slow-release technology, targeting sleep disorders. The tablet incorporates Melatonin ...

This month's "Validation Viewpoint" installment highlights some method validation guidelines used in developing and validating dissolution test procedures. The dissolution performance test is a ...

Though dissolution testing has been under scrutiny, it is still a powerful test method. The dissolution test has been under scrutiny in several areas: the quality-by-design initiative has called for ...

Despite its importance in drug development, dissolution testing still has some limitations, but advances in automation and real-time monitoring are producing promising results. The importance and ...