wxGlade is a GUI builder for wxWidgets/wxPython. It can create Python, C++, Perl, Lisp and XRC output. Unpack the archive to a known location and maybe add it to the path. If you are familiar with git ...
This tutorial shows how to use wxSizer in wxWidgets to create a simple layout. It also shows how to use wxSplitterWindow to create a split view. The links above contain more extensive information ...