The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Bacteriophages have been used therapeutically to treat infectious bacterial diseases for over a century. As ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

Researchers from the Wilmer Eye Institute, Johns Hopkins Medicine Center for Nanomedicine—which designs nanotechnology-based ...

Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.

Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci ...

Explore the role of transcription factor biology in drug discovery and how it impacts our understanding of disease mechanisms ...

Researchers developed LS-170, an inhibitor of the ATAC complex, which suppressed oncogene expression and reduced tumor growth ...

Researchers have identified OTULIN, an immune-regulating enzyme, as a key trigger of tau buildup in the brain. When OTULIN ...

Researchers have examined cellular crosstalk between the gut and liver during sepsis, helping us better understand sepsis ...

In a groundbreaking advancement for cancer treatment, a research team led by Professor Xiang David Li from the Department of Chemistry at The University of Hong Kong (HKU) has made significant strides ...