Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Researchers at The University of Tokyo developed TECHNO, a two-step genome editing strategy that replaces entire mouse loci ...

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...

Our genomes are filled with errors that were once impossible to correct. But in CRISPR, we finally found an extraordinarily ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

Scientists first read the human genome, a three-billion-letter biological book, in April 2003. Since then, researchers have steadily advanced the ability to write DNA, moving far beyond single-gene ...

Discover the innovative TECHNO platform for full-length gene humanisation, enhancing models for human gene function.

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible ...

A recent genetic study has revealed a direct link between Neanderthal ancestry and heightened pain sensitivity in certain ...

A stretch of viral DNA in the mouse genome gives cells in early-stage embryos the potential to become almost any cell type in ...

Modern genetic research reveals that large parts of the human genome come from ancient retroviruses, permanently woven into ...