Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

New nanomaterial passes the blood-brain barrier to reduce damaging inflammation after the most common form of stroke. When ...

Understanding human gene function in living organisms has long been hampered by fundamental differences between species.

Protein scientists could improve reproducibility and coordination across the field by rallying around a small, shared set of ...

“Through CRISPR RNA optimization, we achieved around 59% editing at the TTR locus in our in vitro experiments. In the mouse ...

Respiratory infections are among the leading causes of illness and death in the elderly, driven by immune aging, chronic ...

In a new study, researchers from France have revealed why people with neurofibromatosis type 1 (NF1) often develop serious ...

Researchers demonstrated that declining Hedgehog signaling from Cilk1 loss produces stepwise changes in tooth formation ...

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New research shows that aging blood can accelerate Alzheimer’s-like changes in the brain, while younger blood may offer ...

Introduction: Mouse models play a critical role in cardiology research, offering valuable insights into the molecular mechanisms, genetics, and potential treatments for cardiovascular diseases.