Organic Name Reactions on Instagram: "The Michael addition enables the conjugate (1,4-) addition of carbon nucleophiles to α,β-unsaturated compounds, forming new C–C bonds via attack at the β-carbon. Typical C-nucleophiles include enolates, stabilized carbanions (e.g., malonates, β-dicarbonyls, etc.), and organocuprates. First described by Arthur Michael in the late 19th century, the reaction proceeds through enolate addition to the activated alkene followed by protonation, favoring thermodynami
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Instagramorganic_name_reactions
Organic Name Reactions on Instagram: "The Michael addition enables the conjugate (1,4-) addition of carbon nucleophiles to α,β-unsaturated compounds, forming new
In this post, we'll delve into the world of Michael addition, a fundamental reaction in organic chemistry. We'll explore its mechanism, key characteristics, and applications. From enolate addition to protonation, we'll break down the steps involved in this crucial process. Whether you're a student or a seasoned chemist, this post will help you ...
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