Organic Name Reactions on Instagram: "The Michael addition enables the conjugate (1,4-) addition of carbon nucleophiles to α,β-unsaturated compounds, forming new C–C bonds via attack at the β-carbon. Typical C-nucleophiles include enolates, stabilized carbanions (e.g., malonates, β-dicarbonyls, etc.), and organocuprates. First described by Arthur Michael in the late 19th century, the reaction proceeds through enolate addition to the activated alkene followed by protonation, favoring thermodynami
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Organic Name Reactions on Instagram: "The Michael addition enables the conjugate (1,4-) addition of carbon nucleophiles to α,β-unsaturated compounds, forming new
In this post, we'll delve into the world of Michael addition, a fundamental reaction in organic chemistry. We'll explore its mechanism, key characteristics, and applications. From enolate addition to protonation, we'll break down the steps involved in this crucial process. Whether you're a student or a seasoned chemist, this post will help you ...
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Michael Addition Mechanism
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Every six weeks, up to 32 plasma donors allow Michael Klim to receive vital medication that slows the progression of his rare neurological disorder, chronic inflammatory demyelinating polyneuropathy (CIDP). The Olympic swimming great is a passionate ambassador for Australian Red Cross Lifeblood, which is calling for 9000 new blood and plasma donors this October to meet rising demand. #LifebloodAu | Herald Sun
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