Medications That Can Raise Potassium ⚠️🩺 If you have kidney disease or reduced kidney function, some medications can cause potassium levels to rise. 1️⃣ ACE inhibitors & ARBs Medications like lisinopril, losartan, valsartan, and others help protect the kidneys and heart long term ❤️ However, they can raise potassium, especially if you’re dehydrated, sick, or if kidney function declines. 2️⃣ Potassium-sparing diuretics Drugs like spironolactone and eplerenone are commonly used for heart failure