Skeletal muscle is more than movement — it’s an endocrine organ. When you contract muscle, you’re not just burning calories — you’re releasing myokines. These peptide hormones act as messengers, sending signals to your brain, liver, pancreas, bones, and beyond. They influence: ✔️ Metabolism ✔️ Inflammation ✔️ Insulin sensitivity ✔️ Mood and cognition In other words, contracting muscle speaks to every organ system in your body. The science of myokines is still emerging, but one thing is clear: We